Panama City

Best American Restaurants in Panama City

Looking for the best American restaurants in Panama City? We've gathered 24 spots serving American food in Panama City, ranked by real diner reviews and ratings. Browse photos, check menus, and request a free reservation — all in one place. Updated June 2026.

Unclaimed

Best American Restaurants in Panama City

Millie's Cafe

Panama Cafe

Hooters

International House of Pasta at Laketown

Bikini Bob's Bar

JC's Snack Shop

John Boys

Manatee Neighborhood Bar an Grille

Tatiana's Cafe & Catering

Tom's Hot Dogs

The Bistro Southern Cafeteria

Red's

Red Lobster

Bennigans

Bob Evans Restaurant

Applebee's

O'Charley's

World Famous 23rd Street Waffle Shoppe

g. Foley's

My Best Friend's Kitchen

Corams 231

Big Mama’s country cookin’

Dive Inn Bar & Grill

Stuffy's Cafe

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