Holyoke

Best American Restaurants in Holyoke

Looking for the best American restaurants in Holyoke? We've gathered 14 spots serving American food in Holyoke, ranked by real diner reviews and ratings. Browse photos, check menus, and request a free reservation — all in one place. Updated June 2026.

Unclaimed

Best American Restaurants in Holyoke

Blistie's Inc

110 Grill

Ruby Tuesday

Friendly's

Cajun Cafe and Grill

Uno Pizzeria & Grill - Holyoke

Slainte

Eighty Jarvis Restaurant And Bar

Fast Friends

Fernandez (Family Restaurant)

Friendly's

Mel's Restaurant

Uno Chicago Grill

Yankee Pedlar Inn