Depew

Best Mexican Restaurants in Depew

Looking for the best Mexican restaurants in Depew? We've gathered 6 spots serving Mexican food in Depew, ranked by real diner reviews and ratings. Browse photos, check menus, and request a free reservation — all in one place. Updated June 2026.

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Best Mexican Restaurants in Depew

Margaritas Mexican Cantina

Andale Cantina

[INACTIVE] ANDALE 2 MEXICAN RESTAURANT & BAR

Andale 2 Mexican Restaurant & Bar

Margaritas Mexican Cantina

Moe's Southwest Grill

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