Cape Girardeau

Best American Restaurants in Cape Girardeau

Looking for the best American restaurants in Cape Girardeau? We've gathered 13 spots serving American food in Cape Girardeau, ranked by real diner reviews and ratings. Browse photos, check menus, and request a free reservation — all in one place. Updated June 2026.

Unclaimed

Best American Restaurants in Cape Girardeau

Top of the Marq

Cracker Barrel Old Country Store

O'Charley's

Bob Evans Restaurant

Applebee's

Applebee's

Pilot House Restaurant & Catering

My House Yall

Bel Air Bar and Grill Catering • Warm & Ready Meals

Pilot House

The Pilot House

Steak 'n Shake

Logan's Roadhouse